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[The clinical pharmacology of glycerol guaiacolate ether in the horse–a review].

Abstract: The physical and chemical properties, administration, biotransformation, pharmacological effects, clinical applications, side-effects, toxicity and contraindications of glyceryl guaiacolate ether in the horse are reviewed.
Publication Date: 1986-12-01 PubMed ID: 3553597
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  • English Abstract
  • Journal Article
  • Review

Summary

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This research article provides a comprehensive review on the clinical pharmacology of Glycerol Guaiacolate Ether (GGE) in horses, covering its physical and chemical properties, mode of administration, metabolic transformation, therapeutic impacts, practical uses, side effects, toxicity levels, and contraindications.

Physical and Chemical Properties of Glycerol Guaiacolate Ether

The full description of GGE in the article covers its physical and chemical properties. This might involve various factors such as:

  • Molecular weight
  • Structure
  • Solubility
  • Melting and boiling points
  • Appearance

Administration of Glycerol Guaiacolate Ether

This section details the different methods of administering GGE to horses. It would enlighten acceptable forms and routes of administration, which could comprise:

  • Oral administration
  • Intravenous injection
  • Intramuscular injection

Biotransformation of Glycerol Guaiacolate Ether

This part centers on how GGE is metabolized or biotransformed in horses’ bodies. It might cover stages like absorption, distribution, metabolism, and excretion of GGE.

Pharmacological Effects of Glycerol Guaiacolate Ether

The pharmacological effects of GGE are the therapeutic impacts it has on horses. It might involve the onset of action, peak effect, duration of action, and how this drug targets various body systems in horses.

Clinical Applications of Glycerol Guaiacolate Ether

This involves practical uses of GGE in treating various diseases or conditions in horses. It may involve information about conditions where GGE has been found effective.

Side-Effects of Glycerol Guaiacolate Ether

This section focuses on potential side effects GGE may have on horses upon administration. It could list various potential and reported adverse effects and discomforts that may occur in horses after receiving the medication.

Toxicity of Glycerol Guaiacolate Ether

Here, the article would delve into the toxicity level of GGE, explaining the dose at which it becomes dangerous or potentially fatal to horses. It might also highlight symptoms of overdose.

Contraindications of Glycerol Guaiacolate Ether

This last section will identify conditions under which GGE administration is not advisable. It could encompass factors including specific physiologic conditions, concurrent medications, or any underlying health issues in horses that could lead to serious adverse reactions when GGE is administered.

Cite This Article

APA
Stadler P. (1986). [The clinical pharmacology of glycerol guaiacolate ether in the horse–a review]. J S Afr Vet Assoc, 57(4), 247-249.

Publication

ISSN: 1019-9128
NlmUniqueID: 7503122
Country: South Africa
Language: afr
Volume: 57
Issue: 4
Pages: 247-249

Researcher Affiliations

Stadler, P

    MeSH Terms

    • Animals
    • Guaifenesin / pharmacology
    • Guaifenesin / therapeutic use
    • Guaifenesin / toxicity
    • Horses / metabolism

    Citations

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