The clinical value of whole blood point-of-care biomarkers in large animal emergency and critical care medicine.
Abstract: To summarize the current medical literature and provide a clinical perspective of whole blood point-of-care (POC) biomarkers in large animal emergency and critical care practice. Methods: Original studies, reviews, and textbook chapters in the human and veterinary medical fields. Conclusions: POC biomarkers are tests used to monitor normal or disease processes at or near the patient. In both human and veterinary medicine these tools are playing an increasingly important role in the management of critical diseases. The most important whole blood POC biomarkers available for veterinary practitioners include l-lactate, cardiac troponin I, serum amyloid A, triglyceride, creatinine, and glucose, although many other tests are available or on the horizon. Conclusions: Whole blood POC biomarkers enable clinicians to provide improved management of critical diseases in large animals. These tools are especially useful for establishing a diagnosis, guiding therapy, and estimating disease risk and prognosis.
© Veterinary Emergency and Critical Care Society 2015.
Publication Date: 2015-01-15 PubMed ID: 25590562DOI: 10.1111/vec.12276Google Scholar: Lookup
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- Journal Article
- Review
Summary
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The research paper discusses the significance and advantages of point-of-care (POC) biomarkers in handling emergency and critical diseases in large animals.
Overview of the Study
This research paper is primarily a comprehensive analysis of the existing medical literature, evaluating the practical implications of whole blood Point-Of-Care (POC) biomarkers in large animal emergency and critical care practice.
Methodology
- The authors extracted data from multiple sources including original studies, review articles and textbook chapters across both the human and veterinary medical fields.
- These sources were then analyzed to provide an overview of the current clinical landscape of POC biomarkers application in veterinary medicine.
Conclusion: Significance of Point-Of-Care Biomarkers
- The primary findings indicate that POC biomarkers enable medical professionals to monitor physiological processes and disease progression in real-time, near the patient.
- They are increasingly being used in managing critical and emergency conditions in both human and veterinary medicine.
Key Biomarkers for Veterinary Practitioners
- The research identifies several crucial whole blood POC biomarkers that are particularly beneficial for veterinary practitioners, including l-lactate, cardiac troponin I, serum amyloid A, triglycerides, creatinine, and glucose. Other potential tests also show promise and are under exploration.
Benefits of Whole Blood POC Biomarkers
- Findings suggest that these biomarkers allow clinicians to provide better management of critical diseases in large animals.
- They have proven to be particularly useful for establishing diagnosis, guiding therapy, and estimating disease risk and prognosis.
Cite This Article
APA
Radcliffe RM, Buchanan BR, Cook VL, Divers TJ.
(2015).
The clinical value of whole blood point-of-care biomarkers in large animal emergency and critical care medicine.
J Vet Emerg Crit Care (San Antonio), 25(1), 138-151.
https://doi.org/10.1111/vec.12276 Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.
MeSH Terms
- Animals
- Biomarkers / blood
- Critical Care
- Critical Illness
- Emergencies / veterinary
- Humans
- Point-of-Care Systems
- Troponin I / blood
- Veterinary Medicine
Citations
This article has been cited 2 times.- Goodrich EL, Behling-Kelly E. Particle Size Distribution of Plasma Lipoproteins in Donkeys from Death Valley Compared to a Sampling of Horses. Animals (Basel) 2022 Oct 13;12(20).
- Di Lorenzo E, Rossi R, Ferrari F, Martini V, Comazzi S. Blood L-Lactate Concentration as an Indicator of Outcome in Roe Deer (Capreolus capreolus) Admitted to a Wildlife Rescue Center. Animals (Basel) 2020 Jun 20;10(6).
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