The effect of a compression bandage on the distribution of radiodense contrast medium after palmar digital nerve blocks.
Abstract: Studies have shown proximal diffusion of injected drugs in perineural blocks; such diffusion may affect specificity of the nerve block. Objective: To investigate the effect of a compression bandage applied to the pastern region on proximal diffusion of contrast medium injected over the palmar digital nerves. Methods: Experimental study, randomised cross-over design. Methods: Radiodense contrast medium was injected over the lateral and medial palmar digital nerves of the left front limb of nine mature horses. Each horse was injected on two separate occasions, once with a 5 cm wide compression bandage applied proximal to the injection site and once without. The order of the two treatments was randomised with a wash-out period between treatments of at least 7 days. Radiographs were obtained at 5, 10, 20 and 30 min and distribution of the contrast column assessed. Results: Proximal distribution of the contrast medium was significantly reduced (P<0.01) with compression bandage. Furthermore, the compression bandage inhibited lymphatic drainage of the injected contrast medium. Conclusions: Clinical effect of the differences in diffusion length was not assessed. Conclusions: The compression bandage reduced proximal diffusion and lymphatic drainage of contrast material causing it to stay localised around the injection site. Use of compression bandages could thus result in increased specificity of the nerve block and potentially prolong its effect.
© 2018 EVJ Ltd.
Publication Date: 2018-08-23 PubMed ID: 30071153DOI: 10.1111/evj.13000Google Scholar: Lookup
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- Clinical Trial
- Veterinary
- Journal Article
Summary
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This research investigates how compression bandages applied to a horse’s pastern region affect the distribution of a contrast medium injected over their palmar digital nerves. The study finds that the use of a compression bandage significantly reduces the contrast medium’s proximal diffusion and inhibits lymphatic drainage, possibly leading to a more specific and prolonged effect of a nerve block.
Research Methodology
- The study is experimental in nature, employing a randomised cross-over design. This means that, over different sessions, the same group of horses were subjected to two conditions: once with a compression bandage and once without it, with the order of treatments randomised.
- The sample consisted of nine mature horses. The palmar digital nerves of the left front limb of each horse were injected with a radiodense contrast medium.
- To ensure that previous treatments did not interfere with later ones, a wash-out period of at least 7 days was maintained between treatments.
Procedure and Measurement
- After the injection of the contrast medium, radiographs were obtained at intervals of 5, 10, 20, and 30 minutes to assess the distribution of the contrast column.
- The main variable being measured was the diffusion, or spread, of the contrast medium, particularly its proximal distribution. Proximal, in this context, refers to the direction towards the body from the injection site.
Results and Conclusion
- The results showed a significantly reduced proximal diffusion of the contrast medium with the application of a compression bandage (P<0.01).
- In addition, the compression bandage was found to inhibit the lymphatic drainage of the injected contrast medium, causing it to stay localised around the injection site.
- While the study did not assess the clinical effect of the differences in diffusion length, its results suggest that the use of compression bandages could potentially increase the specificity of the nerve block and possibly extend its effect by confining the contrast material to the local injected area.
Cite This Article
APA
Gylling SMK, Frandsen SS, Østergaard S, Thomsen MH, Christophersen MT, Krüger T, Jacobsen S.
(2018).
The effect of a compression bandage on the distribution of radiodense contrast medium after palmar digital nerve blocks.
Equine Vet J, 51(2), 261-265.
https://doi.org/10.1111/evj.13000 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
- Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Taastrup, Denmark.
MeSH Terms
- Animals
- Compression Bandages / veterinary
- Contrast Media / pharmacokinetics
- Cross-Over Studies
- Female
- Forelimb / innervation
- Horses
- Injections / veterinary
- Iopamidol / analogs & derivatives
- Iopamidol / pharmacokinetics
- Nerve Block / veterinary
- Random Allocation
Grant Funding
- Boehringer Ingelheim Animal Health Nordic
- Lawyer Pernille Skinnerup
- E-vet A/S
- Eickemeyer Denmark
- Farrier Renu00e9 Borup
Citations
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