The effect of intra-articular mepivacaine administration prior to carpal arthroscopy on anesthesia management and recovery characteristics in horses.
Abstract: To evaluate the effects of intra-articular (IA) mepivacaine administration prior to carpal arthroscopy on anesthetic drug requirements, blood pressure support, hemodynamic variables, and quality of recovery in horses. Methods: Experimental, analytical, cohort study. Methods: Twenty-two horses (n = 11 horses/group). Methods: Horses were anesthetized by using the same protocol, but an IA injection of mepivacaine or saline was performed before carpal arthroscopy. End-tidal isoflurane concentration, heart rate, and mean arterial pressure were recorded at specific time points. Quality of recovery was scored by the anesthetist, who was unaware of group assignment. Data were analyzed by using two-way repeated-measures analysis of variance. Results: Mean arterial pressure was higher during joint distension in the control group compared with baseline (7% higher, P = .02) and with the treatment group (10% higher, P = .04). Heart rate was higher in the control group compared with the treatment group during joint distension (8% higher, P = .04) and chip removal (11% higher, P = .03). Heart rate was higher in the control group compared with baseline during chip removal (5.5% higher, P = .04). Two horses in the control group required additional ketamine vs none in the treatment group. Quality of recovery was not different between groups. Conclusions: Intra-articular mepivacaine resulted in fewer detectable reactions to surgical stimulation, with similar recovery scores and blood pressure support requirements. Conclusions: Intra-articular anesthesia prior to arthroscopy can be used safely in the horse and should be considered as a part of balanced anesthetic protocols.
© 2020 American College of Veterinary Surgeons.
Publication Date: 2020-08-31 PubMed ID: 32865260DOI: 10.1111/vsu.13501Google Scholar: Lookup
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- Journal Article
- Randomized Controlled Trial
- Veterinary
Summary
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The research paper investigates the impact of administering mepivacaine directly into a joint before carpal arthroscopy in horses on the requirements for anesthetic drugs, supporting blood pressure, hemodynamic factors, and recovery quality.
Research Methodology
- This experimental, analytical, cohort study involved a sample size of 22 horses. These were divided into two groups, with each comprising 11 horses.
- All horses were anesthetized following the same protocol, but an intra-articular (IA) injection of either mepivacaine or saline was given before carpal arthroscopy.
- Various factors like end-tidal isoflurane concentration, heart rate, and mean arterial pressure were recorded at predetermined intervals.
- The anesthetist, who was not aware of the group assignments, scored the recovery quality of the horses.
- Data collected was analysed using two-way repeated-measures analysis of variance.
Research Findings
- The mean arterial pressure was found to be higher during joint distension in the control group compared to both the baseline (7% higher) and the treatment group (10% higher).
- The heart rate in the control group was higher than the treatment group during joint distension (8% higher) and chip removal (11% higher).
- During chip removal, the heart rate was higher in the control group compared to the baseline by 5.5%.
- The control group had two horses that needed additional ketamine, whereas none of the horses in the treatment group required the same.
- However, the recovery quality between the two groups didn’t show any significant difference.
Research Conclusions
- The study concluded that intra-articular mepivacaine resulted in fewer detectable reactions to surgical stimulation, with similar recovery scores and blood pressure support requirements.
- It was found that intra-articular anesthesia prior to arthroscopy can be used safely in horses and should be considered as a part of balanced anesthetic protocols.
Cite This Article
APA
Gaesser AM, Varner KM, Douglas HF, Barr CA, Hopster K, Levine DG.
(2020).
The effect of intra-articular mepivacaine administration prior to carpal arthroscopy on anesthesia management and recovery characteristics in horses.
Vet Surg, 49(7), 1343-1349.
https://doi.org/10.1111/vsu.13501 Publication
Researcher Affiliations
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
- Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.
MeSH Terms
- Anesthesia / veterinary
- Anesthesia Recovery Period
- Anesthetics, Local / administration & dosage
- Anesthetics, Local / pharmacology
- Animals
- Arthroscopy / veterinary
- Blood Pressure / drug effects
- Cohort Studies
- Female
- Heart Rate / drug effects
- Hemodynamics / drug effects
- Horse Diseases / surgery
- Horses
- Injections, Intra-Articular / veterinary
- Isoflurane / administration & dosage
- Isoflurane / pharmacology
- Ketamine / administration & dosage
- Ketamine / pharmacology
- Male
- Mepivacaine / pharmacology
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This article includes 19 references
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Citations
This article has been cited 1 times.- Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature. Animals (Basel) 2021 Jun 14;11(6).
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