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The Veterinary record1988; 122(5); 106-108; doi: 10.1136/vr.122.5.106

The mucolytic effect of Sputolosin in horses with respiratory disease.

Abstract: The effect of the mucolytic drug Sputolosin on the clinical signs of respiratory disease among 28 matched pairs of horses was examined. Compared with the untreated group, the treated group showed a significant decrease in the frequency of coughing and a decreased time to resolution of both cough and nasal discharge. The results indicate that the drug is potentially useful in the management of respiratory disease characterised by an abnormal or increased production of mucus.
Publication Date: 1988-01-30 PubMed ID: 3363832DOI: 10.1136/vr.122.5.106Google Scholar: Lookup
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  • Journal Article

Summary

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The research paper presents a study about the effectiveness of the mucolytic drug Sputolosin in alleviating symptoms of respiratory diseases among horses.

Overview of the Research

  • This research study aims to understand the impact of the mucolytic drug, Sputolosin, on horses affected by respiratory diseases that typically involve excessive or abnormal mucus production.
  • The subjects of the experiment were 28 pairs of horses. Each pair of horses was carefully matched, meaning they shared similar medical and health backgrounds, to ensure a fair and balanced experimentation process.

Study Design and Execution

  • The 28 pairs of horses were split into two groups – a treatment group that was administered the mucolytic drug Sputolosin, and an untreated group that served as the control group.
  • The main objective was to evaluate the clinical signs of respiratory disease both before and after the administration of the drug, specifically making note of variables such as the frequency of coughing and the time it took for the cough and nasal discharge to resolve.

Results and Findings

  • The results of the study showed a significant decrease in cough frequency among the horses that received Sputolosin. Furthermore, the time taken for both coughing and nasal discharge to resolve was noticeably shorter in the treatment group in comparison to the control group.
  • These results imply that the mucolytic drug Sputolosin is effective in managing the symptoms of respiratory disease in horses, specifically conditions characterized by abnormal or increased production of mucus.

Conclusion

  • The outcomes of the study indicate that Sputolosin could potentially be a beneficial aid in the medical management of respiratory diseases in horses.
  • However, it’s important to note that while the results of this study show some promise, further research involving a larger sample size and more varied test subjects could give a more comprehensive understanding of Sputolosin’s effectiveness.

Cite This Article

APA
Matthews AG, Hackett IJ, Lawton WA. (1988). The mucolytic effect of Sputolosin in horses with respiratory disease. Vet Rec, 122(5), 106-108. https://doi.org/10.1136/vr.122.5.106

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 122
Issue: 5
Pages: 106-108

Researcher Affiliations

Matthews, A G
  • Boehringer Ingelheim Ltd, Bracknell, Berkshire.
Hackett, I J
    Lawton, W A

      MeSH Terms

      • Animals
      • Benzylamines / therapeutic use
      • Cough / drug therapy
      • Cough / veterinary
      • Cyclohexanols / therapeutic use
      • Expectorants / therapeutic use
      • Female
      • Horse Diseases / drug therapy
      • Horses
      • Male
      • Respiratory Tract Diseases / drug therapy
      • Respiratory Tract Diseases / veterinary

      Citations

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