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Tierarztliche Praxis1992; 20(3); 282-286;

[Two rare lens abnormalities in horses].

Abstract: Coloboma and ectopia of the crystalline lens are rarely encountered or diagnosed congenital defects of the equine eye. The clinical and ophthalmoscopic features of a congenital coloboma of the lens in a 3 year old Hanoverian stallion and of an ectopic lens in a 6-month old Hanoverian filly are described and depicted. In the stallion, the lens coloboma was associated with a partial coloboma of the zonules, and in the filly, the ectopic lens was small and spherical (microphakia, spherophakia) and associated with syneresis of and small floaters in the vitreous. Although it cannot be excluded that the ectopic position of the lens may have originated from prenatal uveitis, it was classified as congenital in this case. In both eyes, there were no other clinically detectable congenital defects.
Publication Date: 1992-06-01 PubMed ID: 1496523
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Summary

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The research article presents two cases of uncommon lens deformities in horses – coloboma and ectopia. The study details the clinical and ophthalmoscopic features of these lens defects in a young Hanoverian stallion and filly.

Congenital Coloboma of the Lens

  • In the first case of a 3-year old Hanoverian stallion, the researchers found a congenital coloboma of the lens. Coloboma is a defect that presents as a hole in the structure of the eye, typically in areas like the iris, retina, choroid, or optic disc.
  • The coloboma in this case was associated with a partial coloboma of the zonules, the fibres that hold the lens in place in the eye. As such, the zonules’ partial absence probably contributed to the lens’ abnormal shape.

Ectopic Lens

  • The second part of the study reports on an ectopic lens in a 6-month old Hanoverian filly. Ectopia is a medical term used to describe an organ or body part that is located in an unusual place, in this case, the lens.
  • This filly’s ectopic lens was also observed to be diminutive and spherical, identified as microphakia (small lens) and spherophakia (spherical lens). This ectopic lens was associated with syneresis i.e., the shrinking and condensation in the vitreous, and presence of small floating particles in the vitreous.
  • Although the researchers considered that prenatal uveitis, an inflammation of the middle layer of the eye, might have caused the lens to shift to an ectopic position, they decided to classify it as congenital in this particular case.

Additional Findings

  • In both the studied cases, the researchers did not find any other clinically detectable congenital defects. This reaffirms that these are indeed rare abnormalities and they are the primary focus of this article.

Cite This Article

APA
Gerhards H, Werry H, Deegen E, Köstlin RG. (1992). [Two rare lens abnormalities in horses]. Tierarztl Prax, 20(3), 282-286.

Publication

ISSN: 0303-6286
NlmUniqueID: 7501042
Country: Germany
Language: ger
Volume: 20
Issue: 3
Pages: 282-286

Researcher Affiliations

Gerhards, H
  • Klinik für Pferde der Tierärztlichen Hochschule Hannover.
Werry, H
    Deegen, E
      Köstlin, R G

        MeSH Terms

        • Animals
        • Coloboma / etiology
        • Coloboma / veterinary
        • Ectopia Lentis / etiology
        • Ectopia Lentis / veterinary
        • Female
        • Horse Diseases / congenital
        • Horse Diseases / etiology
        • Horses
        • Lens, Crystalline / abnormalities
        • Male
        • Ophthalmoscopy / veterinary

        Citations

        This article has been cited 1 times.
        1. Esdaile E, Houston K, Till BJ, Sutton RB, Scurrell E, Ling M, Hartley C, Bellone RR. A de novo FBN1 variant likely causes congenital bilateral ectopia lentis in a crossbred horse. Sci Rep 2025 Oct 24;15(1):37238.
          doi: 10.1038/s41598-025-21139-7pubmed: 41136527google scholar: lookup