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Home / Equine Research Bank / Cell Tissue Res / Ultrastructure of rat pinealocytes in vitro: influence of go...
Cell and tissue research1978; 195(3); 547-556; doi: 10.1007/BF00233896

Ultrastructure of rat pinealocytes in vitro: influence of gonadotropic hormones and LH-RH.

Abstract: The influence of gonadotropic hormones on the ultrastructure of rat pinealocytesin short-term organ culture was studied. Human chorionic gonadotropin (HCG), as well as pregnant mare serum gonadotropin (PMSG), caused a marked activation of pinealocytes. An hypothesis is discussed implying the presence of a feedback mechanism between the pineal organ and the hypothalamo-hypophysial system.
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Publication Date: 1978-12-29 PubMed ID: 365351DOI: 10.1007/BF00233896Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article investigates the effect of certain hormones on the ultrastructure of rat pinealocytes in organ culture, with findings suggesting a potential feedback mechanism between the pineal organ and the hypothalamo-hypophysial system.

Objective and Methodology

  • The aim of this research was to study the influence of gonadotropic hormones, specifically human chorionic gonadotropin (HCG) and pregnant mare serum gonadotropin (PMSG), on the ultrastructure of rat pinealocytes in a short-term organ culture.
  • Pinealocytes are the main cells found in the pineal gland, and their changes under influence of the above hormones were reviewed at the ultrastructural level using specific scientific techniques.

Key Findings

  • The study found that both HCG and PMSG caused a marked activation of pinealocytes. This indicates that these hormones have a direct impact on the function of the pineal cells.
  • These findings also imply that the pinealocytes are responsive to gonadotropic hormones, which are typically involved in the regulation of reproductive processes. This is an important biological discovery as it might reveal new interaction and regulation mechanisms between different body systems.

Interpretation and Hypothesis

  • The researchers have interpreted these findings to suggest the presence of a feedback mechanism between the pineal organ (where the pinealocytes are located) and the hypothalamo-hypophysial system.
  • This hypothesis, calling for further research, could contribute in a significant way to our understanding of these body systems and how hormones regulate them.

Significance of the Study

  • The indicated potential interplay between the hypothalamo-hypophysial system and the pineal gland could prove significant in several areas of biological and medical research.
  • This study’s findings could have implications for better understanding of human reproduction, sleep-wake cycle, light perception among other physiological processes where hormones and pinealocytes play a critical role.

Cite This Article

APA
Karasek M, Marek K, Kunert-Radek J. (1978). Ultrastructure of rat pinealocytes in vitro: influence of gonadotropic hormones and LH-RH. Cell Tissue Res, 195(3), 547-556. https://doi.org/10.1007/BF00233896

Publication

Cell and tissue research
ISSN: 0302-766X
NlmUniqueID: 0417625
Country: Germany
Language: English
Volume: 195
Issue: 3
Pages: 547-556

Researcher Affiliations

Karasek, M
    Marek, K
      Kunert-Radek, J

        MeSH Terms

        • Animals
        • Chorionic Gonadotropin / pharmacology
        • Gonadotropin-Releasing Hormone / pharmacology
        • Gonadotropins, Equine / pharmacology
        • Male
        • Mitochondria / ultrastructure
        • Organ Culture Techniques
        • Pineal Gland / ultrastructure
        • Rats

        References

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        Citations

        This article has been cited 6 times.
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