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Veterinary surgery : VS2009; 38(8); 927-933; doi: 10.1111/j.1532-950X.2009.00599.x

Use of propofol-xylazine and the Anderson Sling Suspension System for recovery of horses from desflurane anesthesia.

Abstract: To characterize the behavior of horses recovering in the Anderson Sling Suspension System after 4 hours of desflurane anesthesia and postdesflurane intravenous (IV) administration of propofol and xylazine. Methods: Experimental study. Methods: Healthy horses (n=6), mean+/-SEM age 12.3+/-1.8 years; mean weight 556+/-27 kg. Methods: Each horse was anesthetized with xylazine, diazepam, and ketamine IV and anesthesia was maintained with desflurane in O(2). At the end of 4 hours of desflurane, each horse was positioned in the sling suspension system and administered propofol-xylazine IV. Recovery events were quantitatively and qualitatively assessed. Venous blood was obtained before and after anesthesia for biochemical and propofol analyses. Results: Anesthetic induction and maintenance were without incident. Apnea commonly accompanied propofol administration. All horses had consistent recovery behavior characterized by a smooth, careful, atraumatic return to a standing posture. Conclusions: Results of this study support careful, selective clinical use of desflurane, propofol-xylazine, and the Anderson Sling Suspension System to atraumatically transition horses with high anesthetic recovery risk to a wakeful standing posture. Conclusions: Technique choices to facilitate individualized, atraumatic recovery of horses from general anesthesia are desirable. Use of IV propofol and xylazine to transition horses from desflurane anesthesia during sling recovery to standing posture may facilitate improved recovery management of high-injury risk equine patients requiring general anesthesia.
Publication Date: 2009-12-19 PubMed ID: 20017849DOI: 10.1111/j.1532-950X.2009.00599.xGoogle Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research explores the effects of using the Anderson Sling Suspension System for recovery, alongside propofol-xylazine administration, in horses after 4 hours of desflurane anesthesia. The study supports the idea that this combination could provide a safer and smoother transition from anesthesia to a wakeful state especially in horses that have a high risk during anesthetic recovery.

Methods and Procedures

  • The study was experimental in nature, performed on 6 healthy horses with an average age of 12.3 years and an average weight of 556 kg.
  • Firstly, each horse was anesthetized using xylazine, diazepam, and ketamine, administered intravenously.
  • This was followed by maintaining the anesthesia with the use of desflurane in oxygen for a period of 4 hours.
  • Following the desflurane anesthesia, the horses were put in the Anderson Sling Suspension System. This system is known for lessening the likelihood of injury during recovery from anesthesia.
  • The horses were then administered propofol-xylazine intravenously.
  • Recovery events were both quantitatively and qualitatively assessed during the study. This was performed by monitoring the behavior of the horses and measuring their physical responses. The use of both assessment types ensures a comprehensive view of the recovery process.
  • Venous blood was taken before and after the procedure for biochemical analysis and propofol detection.

Results and Conclusions

  • The induction and maintenance of anesthesia went smoothly without any reported incidents, indicating that this combination of anesthetics was well-tolerated by the horses.
  • Apnea, or temporary cessation of breathing, was commonly observed following the administration of propofol. Though this may seem concerning, apnea following propofol use is a noted and usually non-hazardous side effect.
  • All horses showed consistent recovery behavior characterized by a smooth, careful, and injury-free return to standing.
  • The results support the selective use of desflurane, propofol-xylazine, and the Anderson Sling Suspension System for atraumatic recovery from anesthesia.
  • The study concludes that these techniques could notably assist in a safer recovery process for horses from general anesthesia, particularly those with high injury risk.

This research enhances the understanding of safe recovery practices in equine anesthesia, and can hold valuable implications for veterinary anesthesia techniques. The study’s findings may lead to improved management and lower complications in anesthetic recovery for high-risk equine patients.

Cite This Article

APA
Steffey EP, Brosnan RJ, Galuppo LD, Mama KR, Imai A, Maxwell LK, Cole CA, Stanley SD. (2009). Use of propofol-xylazine and the Anderson Sling Suspension System for recovery of horses from desflurane anesthesia. Vet Surg, 38(8), 927-933. https://doi.org/10.1111/j.1532-950X.2009.00599.x

Publication

ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 38
Issue: 8
Pages: 927-933

Researcher Affiliations

Steffey, Eugene P
  • Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA 95616, USA. epsteffey@ucdavis.edu
Brosnan, Robert J
    Galuppo, Larry D
      Mama, Khursheed R
        Imai, Ayako
          Maxwell, Lara K
            Cole, Cynthia A
              Stanley, Scott D

                MeSH Terms

                • Anesthesia Recovery Period
                • Anesthesia, Inhalation / veterinary
                • Anesthetics, Inhalation
                • Anesthetics, Intravenous
                • Animals
                • Desflurane
                • Female
                • Horses / surgery
                • Immobilization / veterinary
                • Isoflurane / analogs & derivatives
                • Male
                • Monitoring, Physiologic / veterinary
                • Propofol / blood
                • Xylazine