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MMWR. Morbidity and mortality weekly report2012; 61(27); 510-514;

West nile virus disease and other arboviral diseases – United States, 2011.

Abstract: Arthropodborne viruses (arboviruses) are transmitted to humans primarily through the bites of infected mosquitoes and ticks. Symptomatic infections most often manifest as a systemic febrile illness and, less commonly, as neuroinvasive disease (e.g., meningitis, encephalitis, or acute flaccid paralysis). West Nile virus (WNV) is the leading cause of domestically acquired arboviral disease in the United States. However, several other arboviruses also cause seasonal outbreaks and sporadic cases. In 2011, CDC received reports of 871 cases of nationally notifiable arboviral diseases (excluding dengue); etiological agents included WNV (712 cases), La Crosse virus (LACV) (130), Powassan virus (POWV) (16), St. Louis encephalitis virus (SLEV) (six), Eastern equine encephalitis virus (EEEV) (four), and Jamestown Canyon virus (JCV) (three). Of these, 624 (72%) were classified as neuroinvasive disease, for a national incidence of 0.20 per 100,000 population. WNV and other arboviruses continue to cause focal outbreaks and severe illness in substantial numbers of persons in the United States.
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Publication Date: 2012-07-13 PubMed ID: 22785342
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The researchers conducted a study on arboviruses, primarily the West Nile virus, in the United States in 2011. They found that these viruses, which are transmitted through mosquito and tick bites, have been leading to severe illness and local outbreaks.

Research Overview

  • The research focuses on Arthropodborne viruses (arboviruses) which are primarily transmitted to humans via the bites of infected mosquitoes and ticks.
  • The most commonplace manifestation of these symptomatic infections is typically a systemic febrile illness, while less common manifestations include neuroinvasive diseases like meningitis, encephalitis, or acute flaccid paralysis.

West Nile Virus (WNV)

  • The West Nile Virus (WNV) is the leading cause of domestically acquired arboviral disease within the United States. Despite WNV leading the pack, there are several other arboviruses also responsible for seasonal outbreaks and sporadic cases.
  • In 2011, the Centers for Disease Control and Prevention (CDC) received reports of 871 cases of nationally notifiable arboviral diseases, excluding dengue, with etiological agents including WNV (712 cases), La Crosse virus (LACV) (130), Powassan virus (POWV) (16), St. Louis encephalitis virus (SLEV) (six), Eastern equine encephalitis virus (EEEV) (four), and Jamestown Canyon virus (JCV) (three).

Classification of Arboviral Diseases

  • Out of the total reported cases, 624 or about 72% were classified as neuroinvasive disease, translating to a national incidence rate of 0.20 per 100,000 population.
  • The research concludes that WNV and other arboviruses continue to be the cause of severe illnesses to considerable numbers of persons in the United States, leading to focal outbreaks.

Cite This Article

APA
(2012). West nile virus disease and other arboviral diseases – United States, 2011. MMWR Morb Mortal Wkly Rep, 61(27), 510-514.

Publication

MMWR. Morbidity and mortality weekly report
ISSN: 1545-861X
NlmUniqueID: 7802429
Country: United States
Language: English
Volume: 61
Issue: 27
Pages: 510-514

Researcher Affiliations

MeSH Terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Arbovirus Infections / complications
  • Arbovirus Infections / epidemiology
  • Arbovirus Infections / transmission
  • Child
  • Disease Outbreaks
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • United States / epidemiology
  • West Nile Fever / complications
  • West Nile Fever / epidemiology
  • West Nile Fever / transmission

Citations

This article has been cited 21 times.
  1. Zimmerman O, Holmes AC, Kafai NM, Adams LJ, Diamond MS. Entry receptors - the gateway to alphavirus infection. J Clin Invest 2023 Jan 17;133(2).
    doi: 10.1172/JCI165307pubmed: 36647825google scholar: lookup
  2. Rosen SF, Soung AL, Yang W, Ai S, Kanmogne M, Davé VA, Artyomov M, Magee JA, Klein RS. Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination. Genome Med 2022 Sep 24;14(1):108.
    doi: 10.1186/s13073-022-01111-0pubmed: 36153630google scholar: lookup
  3. More S, Bøtner A, Butterworth A, Calistri P, Depner K, Edwards S, Garin-Bastuji B, Good M, Gortázar Schmidt C, Michel V, Miranda MA, Nielsen SS, Raj M, Sihvonen L, Spoolder H, Stegeman JA, Thulke HH, Velarde A, Willeberg P, Winckler C, Baldinelli F, Broglia A, Dhollander S, Beltrán-Beck B, Kohnle L, Morgado J, Bicout D. Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): equine encephalomyelitis (Eastern and Western). EFSA J 2017 Jul;15(7):e04946.
    doi: 10.2903/j.efsa.2017.4946pubmed: 32625598google scholar: lookup
  4. Waddell L, Pachal N, Mascarenhas M, Greig J, Harding S, Young I, Wilhelm B. Cache Valley virus: A scoping review of the global evidence. Zoonoses Public Health 2019 Nov;66(7):739-758.
    doi: 10.1111/zph.12621pubmed: 31254324google scholar: lookup
  5. Kemenesi G, Bányai K. Tick-Borne Flaviviruses, with a Focus on Powassan Virus. Clin Microbiol Rev 2019 Jan;32(1).
    doi: 10.1128/CMR.00106-17pubmed: 30541872google scholar: lookup
  6. Ronca SE, Dineley KT, Paessler S. Neurological Sequelae Resulting from Encephalitic Alphavirus Infection. Front Microbiol 2016;7:959.
    doi: 10.3389/fmicb.2016.00959pubmed: 27379085google scholar: lookup
  7. Basavaraju SV, Kuehnert MJ, Zaki SR, Sejvar JJ. Encephalitis caused by pathogens transmitted through organ transplants, United States, 2002-2013. Emerg Infect Dis 2014 Sep;20(9):1443-51.
    doi: 10.3201/eid2009.131332pubmed: 25148201google scholar: lookup
  8. Garcia MN, Hause AM, Walker CM, Orange JS, Hasbun R, Murray KO. Evaluation of prolonged fatigue post-West Nile virus infection and association of fatigue with elevated antiviral and proinflammatory cytokines. Viral Immunol 2014 Sep;27(7):327-33.
    doi: 10.1089/vim.2014.0035pubmed: 25062274google scholar: lookup
  9. Maximova OA, Speicher JM, Skinner JR, Murphy BR, St Claire MC, Ragland DR, Herbert RL, Pare DR, Moore RM, Pletnev AG. Assurance of neuroattenuation of a live vaccine against West Nile virus: a comprehensive study of neuropathogenesis after infection with chimeric WN/DEN4Δ30 vaccine in comparison to two parental viruses and a surrogate flavivirus reference vaccine. Vaccine 2014 May 30;32(26):3187-97.
    doi: 10.1016/j.vaccine.2014.04.002pubmed: 24736001google scholar: lookup
  10. Staples JE, Shankar MB, Sejvar JJ, Meltzer MI, Fischer M. Initial and long-term costs of patients hospitalized with West Nile virus disease. Am J Trop Med Hyg 2014 Mar;90(3):402-9.
    doi: 10.4269/ajtmh.13-0206pubmed: 24515937google scholar: lookup
  11. Lindsey NP, Staples JE, Delorey MJ, Fischer M. Lack of evidence of increased West Nile virus disease severity in the United States in 2012. Am J Trop Med Hyg 2014 Jan;90(1):163-8.
    doi: 10.4269/ajtmh.13-0432pubmed: 24218412google scholar: lookup
  12. Rossini G, Landini MP, Gelsomino F, Sambri V, Varani S. Innate host responses to West Nile virus: Implications for central nervous system immunopathology. World J Virol 2013 May 12;2(2):49-56.
    doi: 10.5501/wjv.v2.i2.49pubmed: 24175229google scholar: lookup
  13. Lyons J, McArthur J. Emerging infections of the central nervous system. Curr Infect Dis Rep 2013 Dec;15(6):576-82.
    doi: 10.1007/s11908-013-0377-6pubmed: 24136412google scholar: lookup
  14. Phan TG, Vo NP, Boros Á, Pankovics P, Reuter G, Li OT, Wang C, Deng X, Poon LL, Delwart E. The viruses of wild pigeon droppings. PLoS One 2013;8(9):e72787.
    doi: 10.1371/journal.pone.0072787pubmed: 24023772google scholar: lookup
  15. Sung S, Wurcel AG, Whittier S, Kulas K, Kramer LD, Flam R, Roberts JK, Tsiouris S. Powassan meningoencephalitis, New York, New York, USA. Emerg Infect Dis 2013;19(9):1549-51.
    doi: 10.3201/eid1909.121846pubmed: 23969017google scholar: lookup
  16. Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA. Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium. Clin Infect Dis 2013 Oct;57(8):1114-28.
    doi: 10.1093/cid/cit458pubmed: 23861361google scholar: lookup
  17. Duggal NK, D'Anton M, Xiang J, Seiferth R, Day J, Nasci R, Brault AC. Sequence analyses of 2012 West Nile virus isolates from Texas fail to associate viral genetic factors with outbreak magnitude. Am J Trop Med Hyg 2013 Aug;89(2):205-210.
    doi: 10.4269/ajtmh.13-0140pubmed: 23817333google scholar: lookup
  18. . West Nile virus and other arboviral diseases--United States, 2012. MMWR Morb Mortal Wkly Rep 2013 Jun 28;62(25):513-7.
    pubmed: 23803959
  19. Wendell LC, Potter NS, Roth JL, Salloway SP, Thompson BB. Successful management of severe neuroinvasive eastern equine encephalitis. Neurocrit Care 2013 Aug;19(1):111-5.
    doi: 10.1007/s12028-013-9822-5pubmed: 23733173google scholar: lookup
  20. Xu J, Cherry S. Viruses and antiviral immunity in Drosophila. Dev Comp Immunol 2014 Jan;42(1):67-84.
    doi: 10.1016/j.dci.2013.05.002pubmed: 23680639google scholar: lookup
  21. Suthar MS, Diamond MS, Gale M Jr. West Nile virus infection and immunity. Nat Rev Microbiol 2013 Feb;11(2):115-28.
    doi: 10.1038/nrmicro2950pubmed: 23321534google scholar: lookup
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