Arkhiv patologii.
Publisher:
Medicina. Moskva : Media Sfera
Frequency: Six no. a year
Country: Russia (Federation)
Language: Russian
Author(s):
Akademii︠a︡ medit︠s︡inskikh nauk SSSR.
Start Year:1946 -
Identifiers
| ISSN: | 0004-1955 (Print) 2309-1266 (Electronic) 0004-1955 (Linking) |
| NLM ID: | 0370604 |
| (DNLM): | A65910000(s) |
| (OCoLC): | 01778647 |
| Coden: | ARPTAF |
| Classification: | W1 AR8287 |
[Myocardial changes following experimental protein sensitization]. Guinea pigs were sensitized by three subcutaneous injections of 0.1 ml native horse serum at 2-day intervals, 21 days after the third injection the animals developed marked sensitization to this antigen which was manifested by anaphylactic reaction to the subcutaneous challenge with this antigen. At this time, the myocardium of the sensitized animals showed signs of extra- and intracellular oedema, a sharp increase in the number of lysosomes, damage of their membranes, 2 1/2 months after sensitization the animals showed no anaphylactic reaction to the challenge dose of the antigen. There were ...