Autonomic neuroscience : basic & clinical.
Publisher:
Elsevier,
Frequency: Fourteen no, a year, 2000-
Country: Netherlands
Language: English
Author(s):
International Society for Autonomic Neuroscience.
Start Year:2000 -
ISSN:
1566-0702 (Print)
1872-7484 (Electronic)
1566-0702 (Linking)
1872-7484 (Electronic)
1566-0702 (Linking)
Impact Factor
2.7
2022
| NLM ID: | 100909359 |
| (OCoLC): | 44921469 |
| LCCN: | 00233954 |
| Classification: | W1 JO912VD |
Presence of in vitro electrical activity in the ileum of horses with enteric nervous system pathology: equine dysautonomia (grass sickness). Equine dysautonomia (grass sickness) is a frequently fatal disease of horses characterised by intestinal stasis. Interstitial cells of Cajal (ICC) are the pacemakers and mediators of neurotransmission in the gastrointestinal tract. Impaired ICC-mediated control of motility has been implicated in intestinal disorders in laboratory mammals, humans and in equine grass sickness. The aim of this study was to compare the in vitro electrical properties of ileum from grass sickness cases with horses free from gastrointestinal disease. Intracellular microelectrode recordings were made from smooth muscl...
A reduction in interstitial cells of Cajal in horses with equine dysautonomia (grass sickness). Equine dysautonomia (grass sickness) is a common, frequently fatal disease of horses characterised by dysfunction of the gastrointestinal tract. Interstitial cells of Cajal are the c-Kit-immunoreactive cells responsible for the generation of pacemaker activity in gastrointestinal smooth muscle. Impairment of this pacemaker action has been implicated in several motility disorders in humans and laboratory mammals. The aim of this study was to test the hypothesis that changes in interstitial cells of Cajal may be involved in the pathophysiology of the intestinal dysfunction observed in equine gra...