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Biochemistry and molecular biology international.

Discontinued
Periodical
Biochemistry
Molecular Biology
Publisher:
Academic Press,. London ; Philadelphia, PA : Taylor & Francis (1999)
Frequency: Monthly, -1999
Country: England
Language: English
Author(s):
International Union of Biochemistry and Molecular Biology.
Start Year:1993 - 1999
Identifiers
ISSN:1039-9712 (Print)
1039-9712 (Linking)
NLM ID:9306673
(DNLM):SR0076206(s)
(OCoLC):27479240
Coden:BMBIES
Classification:W1 BI635M
Presence and comparison of angiotensin converting enzyme in commercial cell culture sera.
Biochemistry and molecular biology international    March 27, 1999   Volume 47, Issue 1 107-115 doi: 10.1080/15216549900201103
Bramucci M, Miano A, Quassinti L, Maccari E, Murri O, Amici D.This study was conducted to determine the presence of the angiotensin converting enzyme in commercial sera used in cell culture medium. The aim of the research was to bring the presence of proteinases (angiotensin converting enzyme) to cell culture users' knowledge and to give some data for solving problems about the development of peptides as useful drugs. The enzymes, purified from foetal bovine, adult bovine, foetal equine, adult equine, and human sera, showed molecular weights of about 170 kDa. Captopril and lisinopril inhibited enzyme activities at nanomolar concentrations. The enzymes we...