Biological psychiatry.
Publisher:
Plenum Pub. Corp.. New York, NY : Elsevier
Frequency: 24 no. a year, 1990-
Country: United States
Language: English
Author(s):
Society of Biological Psychiatry.
Start Year:1969 -
ISSN:
0006-3223 (Print)
1873-2402 (Electronic)
0006-3223 (Linking)
1873-2402 (Electronic)
0006-3223 (Linking)
Impact Factor
10.6
2022
| NLM ID: | 0213264 |
| (DNLM): | B16940000(s) |
| (OCoLC): | 00855449 |
| Coden: | BIPCBF |
| LCCN: | 78009779 |
| Classification: | W1 BI754L |
High-avidity human serum antibodies recognizing linear epitopes of Borna disease virus proteins. The recent observation that Borna disease virus (BDV)-reactive antibodies from psychiatric patients exhibit only low avidity for BDV antigen called into question their diagnostic value and raised the possibility that antigenically related microorganisms or self antigens caused the production of these antibodies. We further characterized the specificity of these antibodies. Methods: We established a peptide array-based screening test that allows the identification of antibodies directed against linear epitopes of the two major BDV proteins, the nucleoprotein (N) and the phosphoprotein (P). Resu...
Consideration of the relevance of ethological animal models for human repetitive behavioral spectrum disorders. Treatment successes of various stereotyped behaviors in animals and humans has renewed interest in ethologic animal models for the study of psychiatric disorders. This report presents another such behavior occurring in horses to weaving. This anomalous, repetitive, and purposeless behavior draws analogies to human compulsive spectrum behaviors. A "weaver" provided an opportunity to evaluate serotonin, dopamine, and opioid neurotransmitter system contributions by probing each with a selective agent in A-B-A-C-A-D design. The horse was treated in sequential 1-month periods separated by 1-month w...