Biomedical science.
Discontinued
Publisher:
Academy of Sciences of the USSR, Turpin Transactions Ltd., and Pion Ltd.,. London : Academy Of Sciences Of The Ussr, Turpin Transactions Limited And Pion Limited
Frequency: Six no. a year
Country: England
Language: English
Author(s):
Akademii︠a︡ nauk SSSR.
Start Year:1990 - 1991
Identifiers
| ISSN: | 0955-9701 (Print) |
| NLM ID: | 9010320 |
| (DNLM): | SR0066600(s) |
| (OCoLC): | 22155128 |
| Coden: | BSCHE4 |
| Classification: | W1 BI856IL |
Investigation of antigenic structure of attenuated and virulent Venezuelan equine encephalomyelitis virus by means of monoclonal antibodies. A comparative study of the antigenic structure of virulent strains and attenuated vaccine strains of Venezuelan equine encephalomyelitis virus (VEEV) by means of monoclonal antibodies has made it possible to investigate the antigenic structure of the envelope glycoproteins E1 and E2, and to specify their role in the development of antiviral immunity. On the E1 glycoprotein there are five nonoverlapping antigenic sites consisting of eight epitopes that are recognized by monoclonal antibodies; six sites consisting of twenty epitopes were found on the E2 glycoprotein. The monoclonal antibodies ag...