Brain pathology.
Publisher:
International Society of Neuropathology,
Frequency: Quarterly
Country: Switzerland
Language: English
Author(s):
International Society of Neuropathology.
Start Year:1990 -
ISSN:
1015-6305 (Print)
1750-3639 (Electronic)
1015-6305 (Linking)
1750-3639 (Electronic)
1015-6305 (Linking)
Impact Factor
6.4
2023
| NLM ID: | 9216781 |
| (DNLM): | SR0071360(s) |
| (OCoLC): | 24603872 |
| Coden: | BRPAE7 |
| LCCN: | sn 93038293 |
| Classification: | W1 BR114M |
Presence of CD4+ and CD8+ T cells and expression of MHC class I and MHC class II antigen in horses with Borna disease virus-induced encephalitis. Tissues from 9 horses and 1 donkey suffering from natural Borna disease were investigated immunomorphologically. Lymphocytic inflammatory reactions and increased expressions of MHC class I and class II antigen were found in the brain as well as in the trigeminal and olfactory system. Perivascular inflammatory infiltrates were dominated by CD4+ T cells, whereas the majority of CD8+ T cells were disseminated intraparenchymally. No evidence of inflammation was found in the retina. Borna disease virus proteins and nucleic acids were present in the hippocampus, thalamus and medulla oblongata in all...