Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
Publisher:
S. Karger,. Düsseldorf, Germany : Cell Physiol Biochem Press GmbH & Co KG (2019)
Frequency: Six no. a year
Country: Germany
Language: English
Start Year:1991 -
Identifiers
| ISSN: | 1015-8987 (Print) 1421-9778 (Electronic) 1015-8987 (Linking) |
| NLM ID: | 9113221 |
| (DNLM): | SR0068826(s) |
| (OCoLC): | 23603870 |
| Coden: | CEPBEW |
| LCCN: | sn 91033514 |
| Classification: | W1 CE1293 |
Chondrogenic Priming at Reduced Cell Density Enhances Cartilage Adhesion of Equine Allogeneic MSCs – a Loading Sensitive Phenomenon in an Organ Culture Study with 180 Explants. Clinical results of regenerative treatments for osteoarthritis are becoming increasingly significant. However, several questions remain UNANSWERED concerning mesenchymal stem cell (MSC) adhesion and incorporation into cartilage. Methods: To this end, peripheral blood (PB) MSCs were chondrogenically induced and/or stimulated with pulsed electromagnetic fields (PEMFs) for a brief period of time just sufficient to prime differentiation. In an organ culture study, PKH26 labelled MSCs were added at two different cell densities (0.5 x106 vs 1.0 x106). In total, 180 explants of six horses (30 per hor...
Sphere-forming capacity as an enrichment strategy for epithelial-like stem cells from equine skin. Mammal skin plays a pivotal role in several life preserving processes and extensive damage may therefore be life threatening. Physiological skin regeneration is achieved through ongoing somatic stem cell differentiation within the epidermis and the hair follicle. However, in severe pathological cases, such as burn wounds, chronic wounds, and ulcers, the endogenous repair mechanisms might be insufficient. For this reason, exogenous purification and multiplication of epithelial-like stem/progenitor cells (EpSCs) might be useful in the treatment of these skin diseases. However, only few reports a...