The cerebellum.
Publisher:
Martin Dunitz,. New York : Springer (2006)
Frequency: Six no. a year, 2013-
Country: United States
Language: English
Start Year:2002 -
ISSN:
1473-4222 (Print)
1473-4230 (Electronic)
1473-4222 (Linking)
1473-4230 (Electronic)
1473-4222 (Linking)
Impact Factor
3.5
2022
| NLM ID: | 101089443 |
| (OCoLC): | 51268235 |
| Coden: | CERECF |
| LCCN: | 2003213601 |
| Classification: | W1 CE569I |
Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy. Equine cerebellar abiotrophy (CA) is a hereditary neurodegenerative disease that affects the Purkinje neurons of the cerebellum and causes ataxia in Arabian foals. Signs of CA are typically first recognized either at birth to any time up to 6 months of age. CA is inherited as an autosomal recessive trait and is associated with a single nucleotide polymorphism (SNP) on equine chromosome 2 (13074277G>A), located in the fourth exon of TOE1 and in proximity to MUTYH on the antisense strand. We hypothesize that unraveling the functional consequences of the CA SNP using RNA-seq will elucidate the m...