The Chinese journal of physiology.
Publisher:
Chinese Physiological Society.. Mumbai : Wolters Kluwer - Medknow Publications
Frequency: Bimonthly, 2006-
Country: India
Language: English
Author(s):
Zhongguo sheng li xue hui (China : Republic : 1949- )
Start Year:1960 -
ISSN:
0304-4920 (Print)
2666-0059 (Electronic)
0304-4920 (Linking)
2666-0059 (Electronic)
0304-4920 (Linking)
Impact Factor
1.8
2022
| NLM ID: | 7804502 |
| (OCoLC): | 02242131 |
| (DNLM): | C18920000(s) |
| Coden: | CJPHDG |
| Classification: | W1 CH765 |
Pharmacokinetics of intravenously administration of prednisolone in the horse as determined by radioimmunoassay. A radioimmunoassay was developed for prednisolone using IgG purified from rabbit antiserum. The assay was employed to determine the pharmacokinetics of prednisolone following intravenous administration of 450 mg of prednisolone sodium succinate (Solu Delta Cortef) to five adult Thoroughbred horses. The RIA had a sensitivity of 2 ng/ml and was relatively specific. It had cross-reactivity with 21-deoxycortisol (83.3%) cortisol (27.8%), 11-beta-hydroxyprogesterone (39.2%) and 17-hydroxyprogesterone (50%). However, it did not cross-react with naturally occurring steroids (cholesterol, testosterone...