Clinical immunology : the official journal of the Clinical Immunology Society.
Publisher:
Academic Press,
Frequency: Monthly
Country: United States
Language: English
Author(s):
Clinical Immunology Society.
Start Year:1999 -
ISSN:
1521-6616 (Print)
1521-7035 (Electronic)
1521-6616 (Linking)
1521-7035 (Electronic)
1521-6616 (Linking)
Impact Factor
8.6
2022
| NLM ID: | 100883537 |
| (OCoLC): | 39848182 |
| LCCN: | sn 98009273 |
| Classification: | W1 CL715 |
Immune reconstitution prevents continuous equine infectious anemia virus replication in an Arabian foal with severe combined immunodeficiency: lessons for control of lentiviruses. Acute infection with equine infectious anemia virus (EIAV), a lentivirus of horses, results in a persistent high-level viremia in Arabian foals affected with severe combined immunodeficiency (SCID). This observation argues against the idea that the transient nature of acute lentiviral viremia is solely a function of viral population dynamics. To extend these studies, EIAV-specific immune reconstitution was attempted prior to EIAV challenge in two SCID foals, using adoptively transferred virus-stimulated lymphocytes derived from persistently EIAV-infected half sibling donors. Following transfer...