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Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.
Discontinued
Publisher:
Pergamon ;. New York : Elsevier Science (1999)
Frequency: Nine no. a year
Country: United States
Language: English
Start Year:1994 - 1999
Identifiers
| ISSN: | 1367-8280 (Print) 1367-8280 (Linking) |
| NLM ID: | 9516060 |
| (DNLM): | SR0085897(s) |
| (OCoLC): | 32281390 |
| LCCN: | 95647568 |
| Classification: | W1 CO435IH |
The activity of mixed function oxidases, estimated by in vivo antipyrine clearance, is similar in horses and camels. The activity of hepatic mixed function oxidases was compared in horses and camels (Camelus dromedarius) by studying the pharmacokinetics of antipyrine in seven camels and five horses following intravenous administration of a single dose of antipyrine (25 mg/kg). The data obtained (mean +/- SEM and median in brackets) in camels and horses, respectively, were as follows: the elimination half-lives were 3.25 +/- 0.23 (3.19) and 3.09 +/- 0.25 (2.90) hr; the apparent volumes of distribution (area method) were 0.691 +/- 0.045 (0.648) and 0.642 +/- 0.034 (0.676) l/kg; the volumes of distribution at s...
