Current opinion in microbiology.
Publisher:
Current Biology,
Frequency: Bimonthly
Country: England
Language: English
Start Year:1998 -
ISSN:
1369-5274 (Print)
1879-0364 (Electronic)
1369-5274 (Linking)
1879-0364 (Electronic)
1369-5274 (Linking)
Impact Factor
5.4
2022
| NLM ID: | 9815056 |
| (DNLM): | SR0092225(s) |
| (OCoLC): | 38544314 |
| LCCN: | 98-640938 |
| Classification: | W1 CU799AKM |
Borna disease: virus-induced neurobehavioral disease pathogenesis. Studies of the pathogenesis of neurobehavioral diseases following Borna disease virus infections have been increasing rapidly over the past ten years. Recent major advances have included a report of vertical transmission of the virus in its natural host, the horse, and a report of isolation of a novel variant, No/98, in that same species. In rats infected neonatally with the Borna disease virus that lack blood-borne inflammation in the brain, evidence of an "endogenous" brain inflammatory response is abundant, with elevated expression of cytokine and chemokine mRNA. Infection in these rats is ...