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Current pharmaceutical biotechnology.

Periodical, Review
Biotechnology
Pharmacology
Biological Products
Drug Therapy
Publisher:
Bentham Science Publishers,
Frequency: Monthly, 2011-
Country: Netherlands
Language: English
Start Year:2000 -
ISSN:
1389-2010 (Print)
1873-4316 (Electronic)
1389-2010 (Linking)
Impact Factor
2.8
NLM ID:100960530
(OCoLC):45201710
Coden:CPBUBP
LCCN:00243488
Classification:W1 CU79984
Macrocyclic lactones for parasite control in equids.
Current pharmaceutical biotechnology    November 2, 2011   Volume 13, Issue 6 1070-1077 doi: 10.2174/138920112800399310
Lyons ET, Tolliver SC.Macrocyclic lactones (MLs) revolutionized parasite control in horses and other animals. They are unique in that they are effective against arthropods and nematodes. The first of the widely used avermectins was ivermectin. In 1983, it was marketed for use in horses as an injectable formulation but was withdrawn in 1984 after about a year and half on the market because of adverse problems. It was replaced by a paste formulation and an oral/stomach tube liquid formulation. Ivermectin is highly active on bots, ascarids, large and small strongyles, pinworms, strongyloides, stomach worms, and some o...