European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
Publisher:
Elsevier,. Amsterdam : Elsevier Science B.V
Frequency: Fifteen no. a year, 2001-
Country: Netherlands
Language: English
Author(s):
European Federation for Pharmaceutical Sciences.
Start Year:1993 -
ISSN:
0928-0987 (Print)
1879-0720 (Electronic)
0928-0987 (Linking)
1879-0720 (Electronic)
0928-0987 (Linking)
Impact Factor
4.6
2022
| NLM ID: | 9317982 |
| (DNLM): | SR0075711(s) |
| (OCoLC): | 28704641 |
| LCCN: | 94648379 |
| Classification: | W1 EU72DPI |
On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: administration of sodium diatrizoate to the horse. Development of suitable in vitro release models for formulation development as well as quality control purposes has to be initiated in the early design phase of injectable depots. Optimally, construction of an in vitro release model may lead to the establishment of in vitro in vivo correlations. By using a model compound (sodium diatrizoate, DTZ), the purpose of this study was to investigate the possibility of establishing in vitro in vivo relations between the DTZ disappearance profile obtained from the donor compartment of the rotating dialysis cell model and the joint disappearance profile ...