Frontiers in neuroendocrinology.
Publisher:
Raven Press [etc.]. Orlando, FL : Academic Press
Frequency: Quarterly
Country: United States
Language: English
Start Year:1969 -
ISSN:
0091-3022 (Print)
1095-6808 (Electronic)
0091-3022 (Linking)
1095-6808 (Electronic)
0091-3022 (Linking)
Impact Factor
7.4
2022
| NLM ID: | 7513292 |
| (DNLM): | F14280000(s) |
| (OCoLC): | 01388525 |
| Coden: | FNEDA7 |
| Classification: | W1 FR946B |
Dynamics of the regulation of the hypothalamo-pituitary-adrenal (HPA) axis determined using a nonsurgical method for collecting pituitary venous blood from horses. Since 1985, we have applied our nonsurgical technique for collecting pituitary venous (PitVen) blood from ambulatory horses to investigate the regulation of adrenocorticotropic hormone (ACTH) secretion. This method offers particular advantages for studying the hypothalamo-pituitary-adrenal axis since its benign nature enables hypothalamic and pituitary interactions to be monitored without disturbing the animal, and the horse's large blood volume allows 3- to 4-ml samples to be collected as frequently as every 20s for prolonged periods so that the secretion patterns of ACTH and its secretagogue...