Genome biology and evolution.
Publisher:
Oxford University Press
Country: England
Language: English
Author(s):
Society for Molecular Biology and Evolution.
Start Year:2009 -
ISSN:
1759-6653 (Electronic)
1759-6653 (Linking)
1759-6653 (Linking)
Impact Factor
3.3
| NLM ID: | 101509707 |
| (OCoLC): | 430504806 |
| LCCN: | 2009243518 |
Transposable Element Targeting by piRNAs in Laurasiatherians with Distinct Transposable Element Histories. PIWI proteins and PIWI-interacting RNAs (piRNAs) are part of a cellular pathway that has evolved to protect genomes against the proliferation of transposable elements (TEs). PIWIs and piRNAs assemble into complexes that are involved in epigenetic and post-transcriptional repression of TEs. Most of our understanding of the mechanisms of piRNA-mediated TE silencing comes from fruit fly and mouse models. However, even in these well-studied animals it is unclear how piRNA responses relate to variable TE expression and whether the strength of the piRNA response affects TE content over time. Here, w...
Population Variation Reveals Independent Selection toward Small Body Size in Chinese Debao Pony. Body size, one of the most important quantitative traits under evolutionary scrutiny, varies considerably among species and among populations within species. Revealing the genetic basis underlying this variation is very important, particularly in humans where there is a close relationship with diseases and in domestic animals as the selective patterns are associated with improvements in production traits. The Debao pony is a horse breed with small body size that is unique to China; however, it is unknown whether the size-related candidate genes identified in Western breeds also account for the...
A massively parallel sequencing approach uncovers ancient origins and high genetic variability of endangered Przewalski’s horses. The endangered Przewalski's horse is the closest relative of the domestic horse and is the only true wild horse species surviving today. The question of whether Przewalski's horse is the direct progenitor of domestic horse has been hotly debated. Studies of DNA diversity within Przewalski's horses have been sparse but are urgently needed to ensure their successful reintroduction to the wild. In an attempt to resolve the controversy surrounding the phylogenetic position and genetic diversity of Przewalski's horses, we used massively parallel sequencing technology to decipher the complete mitoch...