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Immunodeficiency reviews.
Discontinued
Publisher:
Harwood Academic,. Chur : Harwood
Frequency: Four no. a year
Country: Switzerland
Language: English
Start Year:1988 - 1992
Identifiers
| ISSN: | 0893-5300 (Print) 0893-5300 (Linking) |
| NLM ID: | 9001383 |
| (DNLM): | SR0063021(s) |
| (OCoLC): | 15559491 |
| Coden: | IMMREH |
| Classification: | W1 IM484I |
Domestic animal models of severe combined immunodeficiency: canine X-linked severe combined immunodeficiency and severe combined immunodeficiency in horses. This review describes the clinical, immunologic and pathologic features of two naturally-occurring models of severe combined immunodeficiency (SCID) in domestic animals that represent different forms of human SCID. Canine X-linked SCID (XSCID) has an X-linked recessive mode of inheritance and, as such, represents a model for the most common form of human SCID in the United States. Affected dogs have normal percentages of circulating B cells and low to normal percentages of phenotypically mature, but nonfunctional T cells. Severe combined immunodeficiency in the horse is an autosomal recessive ...
