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Infect Med (Beijing)

Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations.
Infectious medicine    January 17, 2025   Volume 4, Issue 1 100167 doi: 10.1016/j.imj.2025.100167
Parashar B, Malviya R, Sridhar SB, Wadhwa T, Talath S, Shareef J.Eastern equine encephalitis virus (EEEV) is a lethal transmitted by mosquitoes that primarily cycles between birds. Although rare, infections in humans and horses are associated with high mortality rates and severe neurological effects. Climate change appears to be increasing the spread of this virus. This study aims to provide a comprehensive analysis of EEEV, including its transmission dynamics, pathogenesis, induced host immune response, and long-term impacts on survivors. It also highlights the virus's unique immune evasion strategies that complicate disease management and contribute to ...