The International journal of developmental biology.
Publisher:
University of the Basque Country Press,
Frequency: Bimonthly
Country: Spain
Language: English
Start Year:1989 -
ISSN:
0214-6282 (Print)
1696-3547 (Electronic)
0214-6282 (Linking)
1696-3547 (Electronic)
0214-6282 (Linking)
Impact Factor
2.148
2022
| NLM ID: | 8917470 |
| (DNLM): | SR0065608(s) |
| (OCoLC): | 20626707 |
| LCCN: | 96648178 |
| Classification: | W1 IN766GB |
Split immunological tolerance to trophoblast. Split immunological tolerance refers to states in which an individual is capable of mounting certain types of immune responses to a particular antigenic challenge, but is tolerant of the same antigen in other compartments of the immune system. This concept is applicable to the immunological relationship between mother and fetus, and particularly relevant in equine pregnancy. In pregnant mares, antibody responses to paternal foreign Major Histocompatibility Complex class I antigens are robust, while anti-paternal cytotoxic T cell responses are diminished compared to those mounted by non-pregnan...
Experimental embryology of mammals at the Jastrzebiec Institute of Genetics and Animal Breeding. Our Department of Experimental Embryology originated from The Laboratory of Embryo Biotechnology, which was organized and directed by Dr. Maria Czlonkowska until her premature death in 1991. Proving successful international transfer of frozen equine embryos and generation of an embryonic sheep-goat chimaera surviving ten years were outstanding achievements of her term. In the 1990s, we produced advanced fetuses of mice after reconstructing enucleated oocytes with embryonic stem (ES) cells, as well as mice originating entirely from ES cells by substitution of the inner cell mass with ES cells. ...