International journal of nanomedicine.
Publisher:
DOVE Medical Press,
Frequency: Quarterly
Country: New Zealand
Language: English
Author(s):
Institute of Nanotechnology.
Start Year:2006 -
ISSN:
1176-9114 (Print)
1178-2013 (Electronic)
1176-9114 (Linking)
1178-2013 (Electronic)
1176-9114 (Linking)
Impact Factor
8
2022
| NLM ID: | 101263847 |
| (OCoLC): | 173846180 |
| LCCN: | 2007243320 |
| Classification: | W1 IN76948 |
Species-specific identification of collagen components in Colla corii asini using a nano-liquid chromatography tandem mass spectrometry proteomics approach. Colla corii asini (CCA) is a protein-based traditional Chinese medicine made from donkey skins. Because it has the ability to nourish blood, its demand is increasing rapidly. The shortage of donkey skins increases the risk of the adulteration of CCA products with other animal skins. To ensure the drug efficacy and safety of CCA products, a proteomics technique was applied to reveal proteins in the skins of donkey, horse, cattle, and pig. Species-specific peptides for each animal species were predicted using bioinformatics, and their presence in the skins and gelatin samples was examined by nan...