The Journal of clinical investigation.
Publisher:
American Society for Clinical Investigation.. Ann Arbor, MI : American Society for Clinical Investigation (1999)
Frequency: Twenty-four issues a year, 2021-
Country: United States
Language: English
Author(s):
American Society for Clinical Investigation., Central Society for Clinical Research (U.S.)
Start Year:1924 -
ISSN:
0021-9738 (Print)
1558-8238 (Electronic)
0021-9738 (Linking)
1558-8238 (Electronic)
0021-9738 (Linking)
Impact Factor
15.9
2022
| NLM ID: | 7802877 |
| (OCoLC): | 01445593 |
| (DNLM): | J16740000(s) |
| Coden: | JCINAO |
| LCCN: | 27010044 |
| Classification: | W1 JO588H |
In vitro of adenosine on lymphocytes and erythrocytes from horses with combined immunodeficiency. The effect of adenosine on the mitogenic response of peripheral blood lymphocytes (PBL) and on the nucleotide pools of erythrocytes from normal horses, horses heterozygous for the combined immunodeficiency (CID) trait (carriers), and foals with CID was studied. When PBL from normal, carrier, and CID horses were stimulated by phytohemagglutinin (PHA), concanavalin A, or pokeweed mitogen, [3H]thymidine uptake was inhibited by adenosine (0.1 microM) to 1.0 mM) in a dose-dependent manner. Adenosine (100 microM) mediated inhibition of [3H]thymidine uptake was prevented in both normal and carrier ho...
Electrical dose for ventricular defibrillation of large and small animals using precordial electrodes. Electrical ventricular defibrillation of heavy subjects (over 100 kg body weight) is uncommon for the human or any animal species. This paper reports trans-chest ventricular defibrillation of subjects ranging in weight from 2.3 to 340 kg using conventional defibrillation current (heavily damped sine wave) of 0.3-30 ms duration. It was found that a body weight-to-electrical-shock strength relationship exists and can be expressed in terms of either electrical energy or peak current. For the duration of current pulse used clinically (3-10 ms), the relationship between energy requirement and body ...