The journals of gerontology. Series A, Biological sciences and medical sciences.
Publisher:
Gerontological Society of America,. Washington, DC : published on behalf of the Gerontological Society of America by Oxford University Press
Frequency: Monthly, 1999-
Country: United States
Language: English
Author(s):
Gerontological Society of America.
Start Year:1995 -
ISSN:
1079-5006 (Print)
1758-535X (Electronic)
1079-5006 (Linking)
1758-535X (Electronic)
1079-5006 (Linking)
Impact Factor
5.1
| NLM ID: | 9502837 |
| (DNLM): | SR0083315(s) |
| (OCoLC): | 31425404 |
| Coden: | JGASFW |
| LCCN: | 96657473 |
| Classification: | W1 JO669P |
Age-Related Changes in Locomotor Performance Reveal a Similar Pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens. Locomotion is one of the major physiological functions for most animals. Previous studies have described aging mechanisms linked to locomotor performance among different species. However, the precise dynamics of these age-related changes, and their interactions with development and senescence, are largely unknown. Here, we use the same conceptual framework to describe locomotor performances in Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens. We show that locomotion is a consistent biomarker of age-related changes, with an asymmetrical pattern througho...