Journal of tissue engineering.
Publisher:
Sage-Hindawi Access to Research. London : Sage (2011)
Country: England
Language: English
Start Year:2010 -
ISSN:
2041-7314 (Electronic)
2041-7314 (Linking)
2041-7314 (Linking)
Impact Factor
8.2
2023
| NLM ID: | 101550131 |
| (OCoLC): | 706499177 |
| LCCN: | 2011243822 |
Equine lung decellularization: a potential approach for in vitro modeling the role of the extracellular matrix in asthma. Contrary to conventional research animals, horses naturally develop asthma, a disease in which the extracellular matrix of the lung plays a significant role. Hence, the horse lung extracellular matrix appears to be an ideal candidate model for in vitro studying the mechanisms and potential treatments for asthma. However, so far, such model to study cell-extracellular matrix interactions in asthma has not been developed. The aim of this study was to establish a protocol for equine lung decellularization that maintains the architecture of the extracellular matrix and could be used in the future ...