Lab on a chip.
Publisher:
Royal Society of Chemistry,
Frequency: Twenty-four no. a year, 2009-
Country: England
Language: English
Author(s):
Royal Society of Chemistry (Great Britain)
Start Year:2001 -
ISSN:
1473-0197 (Print)
1473-0189 (Electronic)
1473-0189 (Linking)
1473-0189 (Electronic)
1473-0189 (Linking)
Impact Factor
6.1
| NLM ID: | 101128948 |
| (OCoLC): | 48200889 |
| Coden: | LCAHAM |
| LCCN: | 2001257026 |
| Classification: | W1 LA135 |
Correction: The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models. Correction for 'The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models' by Johannes Heidenberger et al., Lab Chip, 2025, 25, 2256-2269, https://doi.org/10.1039/d4lc01078g.
The effect of cyclic fluid perfusion on the proinflammatory tissue environment in osteoarthritis using equine joint-on-a-chip models. Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage degradation, chronic inflammation, and progressive joint dysfunction. Despite rising incidences driven by ageing and increasing obesity, potent treatments remain elusive, exacerbating the socioeconomic burden. OA pathogenesis involves an imbalance in extracellular matrix (ECM) turnover, mediated by inflammatory cytokines and matrix-degrading enzymes, leading to oxidative stress, chondrocyte apoptosis, and ECM degradation. Additionally, synovial inflammation (synovitis) plays a critical role in disease pro...
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract. Rapid, sensitive and specific detection and reporting of infectious pathogens is important for patient management and epidemic surveillance. We demonstrated a point-of-care system integrated with a smartphone for detecting live virus from nasal swab media, using a panel of equine respiratory infectious diseases as a model system for corresponding human diseases such as COVID-19. Specific nucleic acid sequences of five pathogens were amplified by loop-mediated isothermal amplification on a microfluidic chip and detected at the end of reactions by the smartphone. Pathogen-spiked horse nasal swab...