Molecular human reproduction.
Publisher:
Published for the European Society for Human Reproduction and Embryology by Oxford University Press,. Oxford : Oxford University Press for the European Society for Human Reproduction and Embryology
Frequency: Bimonthly, 2004-
Country: England
Language: English
Author(s):
European Society of Human Reproduction and Embryology.
Start Year:1995 -
ISSN:
1360-9947 (Print)
1460-2407 (Electronic)
1360-9947 (Linking)
1460-2407 (Electronic)
1360-9947 (Linking)
Impact Factor
4
2022
| NLM ID: | 9513710 |
| (DNLM): | SR0085210(s) |
| (OCoLC): | 33838450 |
| Coden: | MHREFD |
| Classification: | W1 MO196GW |
Dynamics of extracellular vesicle-coupled microRNAs in equine follicular fluid associated with follicle selection and ovulation. Innumerable similarities in reproductive cyclicity and hormonal alterations highlight the considerable utility of the mare to study aspects of follicular dynamics and reproductive function in view of the largely constricted, human research subjects. The bi-directional communication between the growing oocyte and the surrounding somatic cells embodies the hallmark of mammalian follicular development, partially mediated by extracellular vesicles (EVs) encapsulated with microRNAs (miRNAs) and present in the follicular fluid (FF). Here, we aimed to decipher the dynamics of the miRNAs in EVs from e...
Changes in histone H4 acetylation during in vivo versus in vitro maturation of equine oocytes. Epigenetic modifications are established during gametogenesis and preimplantation embryonic development. Any disturbance of the normal natural environment during these critical phases could cause alterations of the epigenetic signature. Histone acetylation is an important epigenetic modification involved in the regulation of chromatin organization and gene expression. The present study was aimed to determine whether the proper establishment of post-translational histone H4 acetylation at lysine 8 (AcH4K8), 12 (AcH4K12) and 16 (AcH4K16) of equine oocytes is adversely affected during in vitro ma...
Maturation-promoting factor (MPF) and mitogen activated protein kinase (MAPK) expression in relation to oocyte competence for in-vitro maturation in the mare. In the equine species, a large proportion of oocytes fail to complete meiosis during in-vitro culture. The biochemical and molecular basis of this failure is unknown. The meiotic cell cycle is controlled in part by the maturation-promoting factor (MPF) and the mitogen-activated protein kinase (MAPK). In this study, we evaluated the oocyte competence for in-vitro maturation and the expression of MPF components (p34cdc2 and cyclin B) and MAPK after in-vitro culture. The maturation rate was influenced by the culture medium and the physiological stage of the mare at the time of oocyte recovery. We...