Mutation research.
Publisher:
Elsevier,
Frequency: Monthly, 2014-
Country: Netherlands
Language: English
Start Year:1964 -
Identifiers
| ISSN: | 0027-5107 (Print) 1873-135X (Electronic) 0027-5107 (Linking) |
| NLM ID: | 0400763 |
| (OCoLC): | 01590350 |
| (DNLM): | M51460000(s) |
| Coden: | MUREAV |
| LCCN: | 64009436 |
| Classification: | W1 MU973 |
Dose-response of X-irradiated human and equine lymphocytes. We have investigated and compared DNA damage and cell killing induced in human and equine lymphocytes after in vitro X-irradiation. Our data show that the cytogenetic and the lethality effects are both greater in equine lymphocytes, but that the difference is wider for lethality. The ratios between doses inducing the same effect are 1.3, 1.7 and 9.4 for the number of binucleated cells with micronuclei, micronucleus frequency in binucleated cells and DNA synthesis inhibition, respectively. The very different radiosensitivity observed for the two mammalian species encourages us to use their lymp...
Cytogenetic monitoring of farm animals under conditions of environmental pollution. Cytogenetic examinations were carried out in 13 cattle farms, two herds of horses, one stag farm and 13 pig farms in areas with different levels of environmental contamination. The frequency of aberrant cells per 100 mitoses was 3.67 +/- 1.89 in pigs (n = 260) and 4.16 +/- 2.4 in herbivores (n = 497). This is a significant difference (p < 0.01). Ten times higher frequencies of chromatid exchanges were found in pigs. The examined herds were classified into three groups by the level of environmental contamination (satisfactory, impaired and severely impaired environment). Significant differen...