Ophthalmic research.
Publisher:
Karger.
Frequency: Bimonthly
Country: Switzerland
Language: English
Start Year:1970 -
ISSN:
0030-3747 (Print)
1423-0259 (Electronic)
0030-3747 (Linking)
1423-0259 (Electronic)
0030-3747 (Linking)
Impact Factor
2.1
| NLM ID: | 0267442 |
| (DNLM): | O07840000(s) |
| (OCoLC): | 01761331 |
| Coden: | OPRSAQ |
| Classification: | W1 OP238P |
Equine recurrent uveitis–a spontaneous horse model of uveitis. Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody-binding pattern of horses affected by spontaneous recurrent uveitis (ERU) to the retinal proteome. CRALBP also seems to be relevant to human autoimmune uveitis. Proteomic screening of vitreous and retinal samples from ERU diseased cases in comparison to healthy controls has led t...
Technical aspects in ultra-large corneal grafts. The larger the corneal graft, the more difficult is the excision of the button and especially suturing of the graft. The instruments and microsurgical unit are adapted to size and dimensions of animal surgery. The mathematical correlation between the diameter of the graft, the thickness of the cornea, and the length of the wound edges and suturing material can be calculated.