English
French
Pharmacology & therapeutics.
Publisher:
Pergamon Press.
Frequency: Monthly
Country: England
Language: English
Start Year:1979 -
ISSN:
0163-7258 (Print)
1879-016X (Electronic)
0163-7258 (Linking)
1879-016X (Electronic)
0163-7258 (Linking)
Impact Factor
13.5
2022
| NLM ID: | 7905840 |
| (OCoLC): | 04981366 |
| (DNLM): | P11370000(s) |
| Coden: | PHTHDT |
| Classification: | W1 PH283S |
Fumonisins, mycotoxins of increasing importance: their nature and their effects. The fumonisins (FBs) are a group of closely related mycotoxins that are prevalent in maize. They were isolated from strains of Fusarium moniliforme (Sheldon), which were implicated in the aetiology of human oesophageal cancer in the Transkei, South Africa. Their discovery explained the cause of equine encephalomalacia, or "hole in the head" syndrome, when it was found by feeding trials in horses that they elicited the disease. Subsequently, they were found to cause hepatic cancer in rats and pulmonary oedema in pigs, with most animal species tested showing liver and kidney damage. FB1 is the m...
