Proteomics. Clinical applications.
Publisher:
Wiley-VCH,
Frequency: Monthly
Country: Germany
Language: English
Start Year:2007 -
ISSN:
1862-8354 (Electronic)
1862-8346 (Print)
1862-8346 (Linking)
1862-8346 (Print)
1862-8346 (Linking)
Impact Factor
2
2022
| NLM ID: | 101298608 |
| (OCoLC): | 84891600 |
| Coden: | PCARCU |
| LCCN: | 2007243097 |
| Classification: | W1 PR791H |
Systemic Changes in Early Pregnancy in the Mare: An Integrated Proteomic Analysis of Blood Plasma, Histotroph, and Yolk Sac Fluid at Day 14 Post-Ovulation. Embryo-maternal signaling during the establishment of pregnancy in horses remains one of the biggest mysteries in large animal physiology. Early pregnancy loss represents a major source of economic loss to the breeding industry. This study aimed to investigate the systemic changes associated with early pregnancy by mapping the proteome of blood plasma at 14 days in pregnant and non-pregnant mares. Methods: Plasma proteomes were analysed in commercially bred pregnant (n = 17) and non-pregnant (n = 17) Thoroughbred mares at 14 days after ovulation, using high-resolution mass spectrometry. D...
Proteomics in farm animals models of human diseases. The need to provide in vivo complex environments to understand human diseases strongly relies on the use of animal models, which traditionally include small rodents and rabbits. It is becoming increasingly evident that the few species utilised to date cannot be regarded as universal. There is a great need for new animal species that are naturally endowed with specific features relevant to human diseases. Farm animals, including pigs, cows, sheep and horses, represent a valid alternative to commonly utilised rodent models. There is an ample scope for the application of proteomic techniques in f...