Toxicology reports.
Publisher:
Elsevier Ireland Ltd.,
Country: Ireland
Language: English
Start Year:2014 -
Identifiers
| ISSN: | 2214-7500 (Electronic) 2214-7500 (Linking) |
| NLM ID: | 101630272 |
| (OCoLC): | 898215324 |
| LCCN: | 2015243147 |
| Classification: | W1 |
A new method for quantifying causative and diagnostic markers of methylenecyclopropylglycine poisoning. Up to now quantification of hypoglycin A in serum and urine in the range of nmols to μmols per liter plus the measurement of accumulated acyl conjugates have been used for the diagnosis of poisoning by fruits or seeds of in humans and animals. A second poison, methylenecyclopropylglycine, however, is known to occur in this material. The objective of our study was to develop and evaluate a method for the quantification of this compound suitable for test materials obtained from animals and man. Methods: Methylenecyclopropylglycine was extracted from serum and urine of a volunteer by a methanoli...