Analyze Diet

Toxicon: X.

Periodical
Toxicology
Toxins
Biological
Publisher:
Elsevier Ltd.,
Country: England
Language: English
Author(s):
Sociedade Brasileira de Toxinologia,, International Society on Toxinology,, North American Society of Toxinology,
Start Year:2018 -
Identifiers
ISSN:2590-1710 (Electronic)
2590-1710 (Linking)
NLM ID:101741983
(OCoLC):1084240023
LCCN:2019243251
Classification:W1
Stress levels, hematological condition, and productivity of plasma-producing horses used for snake antivenom manufacture: A comparison of two industrial bleeding methods.
Toxicon: X    October 21, 2024   Volume 24 100212 doi: 10.1016/j.toxcx.2024.100212
Arias-Esquivel AM, Moscoso E, Umaña D, Arguedas M, Solano D, Durán G, Gómez A, Gutiérrez JM, León G.The immunization and industrial bleeding of horses are essential stages for producing snake antivenoms. In Costa Rica, the traditional method involves stimulating the antibody response of horses by periodically injecting venoms, collecting hyperimmune plasma over three consecutive bleeding days, and repeating this process every eight weeks. While this method does not cause major physical or hematological issues in horses, the associated stress has not been evaluated. We compared this traditional method with an alternative method that involves injecting venoms, collecting hyperimmune plasma in ...
Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes.
Toxicon: X    April 17, 2023   Volume 18 100158 doi: 10.1016/j.toxcx.2023.100158
Huertas RM, Arguedas M, Estrada JM, Moscoso E, Umaña D, Solano G, Vargas M, Segura Á, Sánchez A, Herrera M, Villalta M, Arroyo-Portilla C....During the production of snake antivenoms, the animals used as immunoglobulin source are subjected to processes that could deteriorate their physical condition. Therefore, these conditions must be carefully designed and validated. In this work, the immunization and bleeding protocols applied to horses used to produce the African polyspecific antivenom EchiTAb-plus-ICP were evaluated regarding their effects on the horses' health. The study focused on horses that had been previously immunized with venoms and then received periodic booster venom injections for antivenom production. It was found t...