Trends in endocrinology and metabolism : TEM.
Publisher:
Elsevier Science Pub. Co.,
Frequency: Ten no. a year
Country: United States
Language: English
Start Year:1989 -
ISSN:
1043-2760 (Print)
1879-3061 (Electronic)
1043-2760 (Linking)
1879-3061 (Electronic)
1043-2760 (Linking)
Impact Factor
10.9
2022
| NLM ID: | 9001516 |
| (DNLM): | SR0065634(s) |
| (OCoLC): | 19370142 |
| Coden: | TENME4 |
| Classification: | W1 TR3409 |
Animal models of Cushing’s disease. Cushing's disease, defined as hyperadrenocorticism resulting from excessive secretion of pituitary ACTH, occurs spontaneously and quite commonly in dogs and horses. In dogs, as in humans, the disease is usually associated with a small tumor of the pituitary pars distalis. However, the disease may arise occasionally (dogs) or exclusively (horses) from tumors or hyperplasia of the pituitary pars intermedia. In dogs, pars intermedia tumors may arise from one of two proopiomelanocortin-containing cell types that are present in normal tissue.