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Turkish journal of medical sciences.
Publisher:
Scientific and Technical Research Council of Turkey,
Frequency: Bimonthly,
Country: Turkey
Language: English
Author(s):
Türkiye Bilimsel ve Teknik Araştırma Kurumu.
Start Year:1994 -
Identifiers
| ISSN: | 1300-0144 (Print) 1303-6165 (Electronic) 1300-0144 (Linking) |
| NLM ID: | 9441758 |
| (DNLM): | SR0082401(s) |
| (OCoLC): | 30839318 |
| Classification: | W1 TU569EM |
History repeats itself: horse originated hyperimmune sera production against SARS CoV-2. SARS-CoV-2 disease was announced as a pandemic by The World Health Organization in early 2020. It is still threatening the world population. Here, we aimed to produce hyperimmune sera that contain immunoglobulin G and F(ab')2 fragments sourced from horse antibodies as an urgent response to the pandemic. SARS-CoV-2 was produced and inactivated with three different methods [formaldehyde (FA), formaldehyde, and binary ethylene amine (FA + BEI), and heat treatment]. After in vitro inactivation control, immunogens were mixed with Freund’s adjuvant, thereafter horses (n: 2 for FA, 4 for FA + BEI, ...
Horse allergen sensitivity and respiratory symptoms among horse farm workers. Sensitivity and symptoms related to animal proteins have been investigated in various occupational groups. However, data from horse farm workers are limited. We aimed to determine horse allergen sensitivity in the horse farm workers, and to evaluate its relationship with respiratory symptoms and functional parameters. A total of 110 subjects were enrolled in the study. The study group consisted of 80 horse farm workers. Face-to-face surveys, skin prick tests (SPT), and pulmonary function tests (PFT) were performed in the study group. Control group consisted of 30 healthy subjects. SPT and PFTs...
