World journal of experimental medicine.
Publisher:
Baishideng Publishing Group Co., Limited. Pleasanton, CA : Baishideng Publishing Group (2014)
Frequency: Four issues a year, 2013-
Country: United States
Language: English
Start Year:2011 -
Identifiers
| ISSN: | 2220-315X (Electronic) 2220-315X (Linking) |
| NLM ID: | 101618808 |
| (OCoLC): | 867845841 |
| LCCN: | 2014243038 |
Recent clinical trials of cancer immunogene therapy in companion animals. This mini-review presents the results of veterinary clinical trials on immunogene therapy published from 2014 to 2016. A variety of tumors, among them melanoma (canine and equine), mastocytoma (canine), mammary adenocarcinoma (canine) and fibrosarcoma (feline) were treated by using diverse strategies. Non-viral vectors were usually employed to transfer genes of cytokines, suicide enzymes and/or tumor associated antigens. In general terms, minor or no adverse collateral effects were related to these procedures, and treated patients frequently improved their conditions (better quality of life, d...