Xenotransplantation.
Publisher:
Munksgaard,. Copenhagen : Munksgaard International Publishers
Frequency: Bimonthly, 2002-
Country: Denmark
Language: English
Start Year:1994 -
ISSN:
0908-665X (Print)
1399-3089 (Electronic)
0908-665X (Linking)
1399-3089 (Electronic)
0908-665X (Linking)
Impact Factor
3.9
2022
| NLM ID: | 9438793 |
| (DNLM): | SR0079333(s) |
| (OCoLC): | 31500231 |
| Classification: | W1 XE12 |
Glycosphingolipids of porcine, bovine, and equine pericardia as potential immune targets in bioprosthetic heart valve grafts. Pericardial tissue from various animal species is utilized for the production of the bioprosthetic heart valves (BHV) used clinically. Experimental data show that the eventual breakdown of BHV is partly due to immunological interactions with carbohydrate tissue antigens. To understand these processes, we have examined the glycolipid-based carbohydrate antigens in naïve porcine, bovine, and equine pericardia. Total non-acid and acid glycosphingolipid fractions were isolated from porcine, bovine, and equine pericardia, and individual glycolipid compounds were characterized by thin-layer chromat...