Lipoproteins in horses are complex molecules composed of lipids and proteins that are essential for the transport of lipids through the bloodstream. They are involved in various physiological processes, including the metabolism of fats and the maintenance of cellular function. In horses, lipoproteins can be classified into different types based on their density, such as high-density lipoproteins (HDL) and low-density lipoproteins (LDL). These molecules are significant for understanding equine metabolism and health, as they can influence the development of metabolic disorders and cardiovascular conditions. This page compiles peer-reviewed research studies and scholarly articles that investigate the structure, function, and clinical relevance of lipoproteins in equine species.
McCann ME, Watson TD, Boudinot FD, Moore JN.We evaluated the pharmacokinetics of IV administered sodium heparin and the pharmacodynamic effect of heparin on lipoprotein lipase (LPL) activity. Horses were allotted to 3 groups. Plasma samples were obtained from each horse before and at various times for 6 hours after heparin administration for determination of heparin concentration, LPL activity, and activated partial thromboplastin time (APTT). The disposition of heparin was dose dependent. The area under the plasma heparin concentration vs time curve (AUC) increased more than proportionally with dose, indicating that heparin elimination...
Rółkowski R, Worowski K, Skrzydlewski Z.Antiheparin activity of plasma of different species of vertebrates depends to a large extent on contents of low density lipoproteins (LDL). High antiheparin activity of the blood plasma of chicken and human corresponds to high contents of LDL and low antiheparin activity of the blood plasma of horse, cow, sheep, dog and pig corresponds to decreased contents of these proteins. Differences in the contents of fibrinogen, acid alfa1-glycoproteins, globulins, alkaline proteins and antithrombin III activity have smaller influence on antiheparin activity in the blood plasma of the examined animals.
