Topic:Mebendazole
Mebendazole is an anthelmintic medication used to treat parasitic worm infections in horses. It belongs to the benzimidazole class of drugs and functions by inhibiting the uptake of glucose by the parasites, leading to their eventual death. Mebendazole is effective against a range of gastrointestinal nematodes, including large and small strongyles. Its use in equine medicine is part of broader parasite management strategies aimed at maintaining horse health and performance. This page compiles peer-reviewed research studies and scholarly articles that explore the efficacy, pharmacokinetics, and safety of mebendazole in horses, as well as its role in integrated parasite control programs.
Effectiveness of oxibendazole against benzimidazole-resistant strongyles in horses. Twenty-eight horses with a residual burden of strongyle eggs in the faces after treatment with mebendazole (MBZ) paste were treated with a suspension of either MBZ or oxibendazole (OBZ). Fecal samples were collected before and 14 days after these treatments. The number of strongyle eggs/g (epg) of feces for each horse was estimated using the Cornell-McMaster dilution and the Cornell-Wisconsin double centrifugation procedures. The epg for each horse was transformed using log (x + 1) and in an analysis of variance of the reduction in egg count for each horse on the logarithmic scale, there was a...
Prevalence and treatment of tapeworms in horses. A study was initiated to determine the prevalence of tapeworms in horses in Southern Ontario and to investigate the efficacy of pyrantel pamoate, niclosamide and mebendazole. Fecal samples were taken from 580 horses of various breeds, ages and sexes in 24 locations and Anoplocephala perfoliata was found in 13.6%. This was regarded as a minimum, the true rate being probably significantly higher and the reasons for this are discussed. A brief review of the life cycle and effects of tapeworms in horses and a comparison of two flotation techniques for the diagnosis of A. perfoliata eggs in feces i...