Metabolic acidosis in horses is a condition characterized by an imbalance in the body's acid-base status, resulting in a lower than normal blood pH. This condition arises when there is an accumulation of acid or a significant loss of bicarbonate in the body, which can occur due to various factors such as intense exercise, gastrointestinal disturbances, or renal dysfunction. In horses, metabolic acidosis can affect cellular function and overall metabolic processes. The condition is typically assessed through blood gas analysis, measuring parameters such as blood pH, bicarbonate levels, and carbon dioxide concentration. This page compiles peer-reviewed research studies and scholarly articles that explore the causes, physiological impacts, and management strategies of metabolic acidosis in equine health.
Haugaard SL, Nissen SD, Schneider MJ, Birk JB, Carstensen H, Hopster-Iversen C, Altıntaş A, Barrès R, Kjøbsted R, Wojtaszewski JFP, Herum KM....High recurrence rates after atrial fibrillation (AF) treatment may be driven by myocardial changes induced by the arrhythmia itself. Understanding the molecular mechanisms behind these changes is crucial for developing targeted therapies and improving outcomes. Objective: To characterise the cardiac transcriptome of healthy horses and explore transcriptional changes associated with persistent AF (naturally occurring and tachypacing-induced). Methods: Case-control study. Methods: RNA-sequencing was performed on atrial and ventricular tissue samples collected from six horses with naturally occur...