Topic:Micropolyspora faeni
Micropolyspora faeni is a thermophilic actinomycete commonly found in moldy hay and other organic matter. It is known to be a significant environmental factor in the development of respiratory conditions in horses, particularly in those stabled in environments with poor ventilation. Exposure to Micropolyspora faeni can lead to hypersensitivity reactions in the equine respiratory system, contributing to conditions such as recurrent airway obstruction (RAO), also known as heaves. This page gathers peer-reviewed research studies and scholarly articles that explore the prevalence, pathogenesis, and impact of Micropolyspora faeni on equine respiratory health, as well as management practices to mitigate exposure.
Airborne dust and aeroallergen concentration in a horse stable under two different management systems. Airborne dust concentration (ADC) was measured in 2 different horse management systems using an Andersen cascade impactor in the box-stall, and a personal Marple cascade impactor attached to the halter to measure ADC in the breathing zone. The levels of aeroallergens implicated in chronic obstructive pulmonary disease were measured by radioallergosorbent-inhibition immunoassay. A conventional management system (System C) utilising hay feed and straw bedding, and a recommended environment (System R) utilising wood shaving bedding and a complete pelleted diet were studied. In the stall, total an...
The effects of sodium cromoglycate on antigen inhalation challenge in two horses affected with chronic obstructive pulmonary disease (COPD). 80 mg sodium cromoglycate (SCG) was administered by inhalation to two COPD-affected animals known to have respiratory hypersensitivity to Micropolyspora faeni. SCG treatment 20-30 minutes prior to inhalation challenge with M. faeni prevented exacerbation of respiratory disease, usually seen 4-8 hours after challenge. duration of protection against antigen challenge after a single SCG treatment was 4-5 days. The duration of protection was not prolonged by reducing the frequency of antigen challenge. Multiple antigen challenge, using M. faeni and Aspergillus fumigatus, shortened the protective p...