[A literature review of equine piroplasmosis after an episode of acute babesiosis in a Dutch Standardbred foal after a stay in Normandy].
Abstract: Piroplasmosis, a disease endemic to most tropical and subtropical areas, appears to be spreading to more temperate zones. This article gives a review of equine piroplasmosis and describes an acute case of infection with Babesia caballi in a Dutch Standard bred foal after a short stay at a stud in Normandy (France). A 3-month-old stallion foal was presented with lethargy, fever of 41 degrees C, and pale mucosal membranes. Haematology revealed a low packed cell volume (14 l/l) leucytosis (25 G/l) and a high blood urea nitrogen concentration (20.1mmol/l). Infection with B. caballi was diagnosed on the basis of Giemsa staining blood smears and was confirmed by polymerase chain reaction in combination with RLB. Treatment with imidocarb dipropionate and a blood transfusion resolved the haemolytic crisis.
Publication Date: 2005-12-21 PubMed ID: 16363205
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Summary
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The research article focuses on equine piroplasmosis, a disease more common in tropical and subtropical regions, but seemingly spreading to temperate zones. It explores an acute case in a Dutch Standardbred foal that had visited Normandy, France, and sheds light on the treatment methods used to resolve the issue.
Equine Piroplasmosis Overview
- Equine Piroplasmosis is a disease predominantly found in equines and is generally found in tropical and sub-tropical regions. It is caused by protozoan parasites that affect the red blood cells.
- However, there have been recent signs of the disease spreading into more temperate climate zones, as highlighted by the research.
Case Study Observations
- The case study in this research pertains to a 3-month-old Dutch Standardbred foal, which had just returned to its home country after a short stay at a stud in Normandy, France.
- Upon return, the foal exhibited symptoms such as lethargy and fever (of up to 41 degrees Celsius) and had pale mucosal membranes, which are often key indicators of serious disease.
Diagnostic Procedures
- The researchers observed a low packed cell volume, leucytosis, and high blood urea nitrogen concentration in the haematology results, which all suggested an issue with red blood cells.
- Using a staining method called Giemsa Staining – which helps to visualize and identify organisms inside cells – on blood smears, the scientists were able to diagnose the foal with B.caballi infection, which is a type of piroplasmosis.
- A Polymerase Chain Reaction was used in combination with Reverse Line Blot. The PCR amplifies the DNA sample, while the RLB identifies the species of the parasite. This helped to confirm the diagnosis.
Treatment and Recovery
- After the diagnosis, the foal was treated with Imidocarb Dipropionate, a drug known to be effective against protozoal infections such as piroplasmosis, and a blood transfusion to deal with the hemolytic crisis.
- The treatment was successful, and the foal was able to recover from the infection.
Cite This Article
APA
Butler CM, van Gils JA, van der Kolk JH.
(2005).
[A literature review of equine piroplasmosis after an episode of acute babesiosis in a Dutch Standardbred foal after a stay in Normandy].
Tijdschr Diergeneeskd, 130(23), 726-731.
Publication
Researcher Affiliations
- Hoofdafdeling Gezondheidszorg Paard, Discipline Inwendige Ziekten, Faculteit der Diergeneeskunde, Universiteit Utrecht, Yalelaan 16, 3508 TD Utrecht.
MeSH Terms
- Animals
- Antiprotozoal Agents / therapeutic use
- Babesiosis / diagnosis
- Babesiosis / pathology
- Babesiosis / therapy
- Babesiosis / veterinary
- Blood Transfusion / veterinary
- Blood Urea Nitrogen
- Diagnosis, Differential
- France
- Hematocrit / veterinary
- Hematologic Tests / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / pathology
- Horse Diseases / therapy
- Horses
- Imidocarb / therapeutic use
- Leukocytosis / diagnosis
- Leukocytosis / drug therapy
- Leukocytosis / pathology
- Leukocytosis / veterinary
- Male
- Netherlands
- Travel
- Treatment Outcome
Citations
This article has been cited 2 times.- Tirosh-Levy S, Gottlieb Y, Fry LM, Knowles DP, Steinman A. Twenty Years of Equine Piroplasmosis Research: Global Distribution, Molecular Diagnosis, and Phylogeny.. Pathogens 2020 Nov 8;9(11).
- Ionita M, Nicorescu IM, Pfister K, Mitrea IL. Parasitological and molecular diagnostic of a clinical Babesia caballi outbreak in Southern Romania.. Parasitol Res 2018 Jul;117(7):2333-2339.
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