A preliminary study of silver sodium zirconium phosphate polyurethane foam wound dressing on wounds of the distal aspect of the forelimb in horses.
- Journal Article
- Randomized Controlled Trial
- Research Support
- Non-U.S. Gov't
Summary
The research article investigates whether the use of a wound dressing made from a material called silver sodium zirconium phosphate polyurethane foam improves healing in wounds on horse’s limbs, compared to a conventional absorbent dressing.
Study Methodology
This was a controlled and randomized experimental study involving five adult Quarter Horse and Thoroughbred horses. A wound of fixed size (6.25 cm2) was made on a specific part of each horse’s forelimb. One wound was treated with the special polyurethane foam dressing (termed SPF dressing), and the other with a standard non-adherent absorbent dressing. For both types, dressings were changed every three days over a period of 60 days.
- Granulation tissue in the wounded area was examined and rated in terms of severity every three days.
- The precise area of the wound was measured every six days.
- A culture was taken from the wound bed every 12 days to assess bacterial contamination.
Outcomes
Throughout the first 30 days and over the complete 60-day trial, wounds that had been dressed with SPF showed a more significant decrease in size and granulation tissue scores than those treated with the standard dressing. Despite this, the times taken for complete healing to be achieved did not differ significantly between the SPF-treated wounds and the controls. Bacterial contamination was discovered in all wounds, regardless of treatment type, at various points over the course of the research.
Conclusions and Implications
The results indicate that the SPF dressing showed incremental improvements in a couple of wound healing factors as compared to the control dressing, particularly in the initial 30-day period. Therefore, the authors conclude that SPF dressing might be a useful tool in the early stages of treating wounds on a horse’s lower limb. Suggestions have been made for additional studies to further understand its effects on wound healing over time and at a cellular level and to assess its suitability in an actual clinical setting.
Cite This Article
Publication
Researcher Affiliations
- William R. Pritchard Veterinary Medical Teaching Hospital, University of California-Davis, Davis, California.
MeSH Terms
- Animals
- Bandages / veterinary
- Female
- Forelimb / injuries
- Horses / injuries
- Male
- Phosphates / administration & dosage
- Polyurethanes / administration & dosage
- Silver Compounds / administration & dosage
- Surgical Wound Infection / microbiology
- Surgical Wound Infection / pathology
- Surgical Wound Infection / prevention & control
- Surgical Wound Infection / veterinary
- Treatment Outcome
- Wound Healing
- Zirconium / administration & dosage
Citations
This article has been cited 2 times.- Ribeiro G, Carvalho L, Borges J, Prazeres J. The Best Protocol to Treat Equine Skin Wounds by Second Intention Healing: A Scoping Review of the Literature. Animals (Basel) 2024 May 18;14(10).
- Helal IE, Al-Abbadi HA, El-Daharawy MH, Ahmed MF. Enhancement of chronic wound healing with maltodextrin/ascorbic acid gel: a clinical evaluation of distal limb wounds in horses. J Anim Sci Technol 2022 Sep;64(5):997-1007.